Harrison's Principles of Internal Medicine, Twenty-Second Edition

by Anthony S. Fauci

First published 2025

Dr. Anthony Harrison navigates the sterile corridors of Internal Medicine General Hospital, where diagnostic protocols have become something far stranger than he learned in residency. The twenty-second edition of treatment guidelines arrives with modifications that blur the line between healing and something else entirely. Harrison discovers that the two-volume manual contains procedures that seem to anticipate diseases before they manifest. His patients present with conditions that match the text perfectly, down to symptoms that should not yet exist. As Harrison delves deeper into the revised protocols, he realizes the guidelines are not just describing medicine but actively shaping it. The hospital becomes a testing ground where theory and practice merge in unsettling ways. Harrison must choose between following the increasingly bizarre directives or abandoning everything he believed about the practice of medicine. The stakes rise as he uncovers the true purpose behind the new edition.

Genres: science, medical, non-fiction, academic

Vibes: thought-provoking

Period: 20th-Century, 21st-Century

Hardcover · McGraw Hill / Medical

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